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辐射暴露在多重遗传性异位症:一个回顾性审查
Nolan D Farrell1, Jennings H Dooley2, Benjamin W Sheffer1
1The University of Tennessee Health Science Center - Campbell Clinic Department of Orthopaedic Surgery and Biomedical Engineering, Memphis, TN, USA.
Journal of orthopaedics
|May 26, 2023
概括
患有多重遗传性外位症 (MHE) 的患者从诊断成像中经历了显著的电离辐射暴露. 年龄在10-24岁的人获得最高剂量,需要仔细证明X射线图的合理性,因为儿科患者的癌症风险增加.
科学领域:
- 医疗成像医学成像
- 辐射瘤学 辐射瘤学
- 儿科瘤学 儿科瘤学
背景情况:
- 多重遗传外位症 (MHE) 需要频繁的诊断和治疗电离辐射暴露.
- 儿科患者更容易受到辐射的不良影响,包括增加癌症风险.
- 在MHE患者中量化累积辐射剂量至关重要,但没有充分记录.
研究的目的:
- 为了量化MHE患者在五年内累积的电离辐射暴露.
- 在MHE诊断和治疗中识别辐射暴露的来源和模式.
- 评估MHE患者中与年龄相关的辐射暴露差异.
主要方法:
- 在37名MHE患者 (2015-2020年) 中,对1200个成像研究 (放射,CT,核医学,光学) 的回顾性分析.
- 研究被分为与MHE相关的 (976) 和与MHE无关的 (224).
- 计算每位患者平均累积辐射剂量,并分析特定年龄的暴露.
主要成果:
- 每个MHE患者的平均累积辐射剂量为5.23mSv.
- 放射照片是MHE相关辐射暴露的最大来源.
- 与较年轻儿童相比,10-24岁的患者接受了显著更多的成像研究和更高的辐射剂量 (P=0.016).
结论:
- MHE患者经历大量的电离辐射暴露从连续诊断成像.
- 青少年和年轻成年人 (10-24岁) 被不成比例地暴露.
- 在儿科MHE患者中,由于辐射敏感性和癌症风险增加,放射性使用的合理性至关重要.
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