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Updated: Jul 29, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants

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在MRGPRX2信号传递过程中涉及lysyl-tRNA合成酶和MITF通路

Yanru Guo1,2, Laia Ollé1,2, Elizabeth Proaño-Pérez1,2,3

  • 1Biochemistry and Molecular Biology Unit, Biomedicine Department, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.

Frontiers in immunology
|May 26, 2023
PubMed
概括

这项研究表明,激活MRGPRX2受体会导致微相关转录因子 (MITF) 活性增加,这对于巨细胞脱粒化至关重要. 抑制这种途径可以治疗与MRGPRX2相关的疾病.

关键词:
这就是LysRSRS.美国MITF MITF在MRGPRX2中使用.药物不良反应 药物不良反应巨细胞的脱粒化

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