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农作物,宿主和肠道微生物群的变异影响精准营养:蓝的一个例子

Connie M Weaver¹, Mario G Ferruzzi², Maria Maiz³

¹School of Exercise and Nutritional Science, San Diego State University, San Diego, CA 92182, USA.

Antioxidants (Basel, Switzerland)

|May 27, 2023

概括

蓝显示出改善骨健康和影响肠道微生物组合的潜力. 不同的蓝品种和剂量会影响多的生物可用性和肠道细菌,为精确的营养策略提供信息.

科学领域:

营养科学营养科学
微生物学微生物学
遗传学是一个遗传学.

背景情况:

流行病学和临床前研究表明,富含多的水果,特别是蓝,与改善骨健康之间存在联系.
与年龄相关的骨质损失是一个重大的健康问题,了解饮食干预措施至关重要.

研究的目的:

研究不同蓝基因型和剂量的对骨健康和肠道微生物群的影响.
确定特定的蓝品种和消费水平,有效减轻与年龄相关的骨质损失.

主要方法:

利用主要成分分析来选择蓝基因型,具有明显的安东素样式.
进行了体外,临床前 (老鼠模型) 和临床研究,以评估多的生物可用性和肠道微生物组的变化.
采用阿尔法和β多样性分析来评估肠道微生物群的变化,以应对蓝的消费.

主要成果:

总含量并不能始终预测大鼠中的多生物可用性;个体化合物的生物可用性因基因型而异.
蓝的消费,特别是不同剂量的蓝,显著改变了大鼠的肠道微生物组概况.
确定了特定的细菌种群,包括Prevotellaceae_UCG-001和Coriobacteriales,在蓝摄入后增加,突出显示它们在多代谢中的作用.

结论:

蓝的基因型和剂量是影响多生物可用性和肠道微生物组调节的关键因素.
这些发现支持肠道微生物群在多代谢中的作用,并表明针对精密营养的蓝培育有潜力.
这项研究为开发使用特定蓝品种的饮食策略提供了基础,以支持骨健康和肠道健康.

关键词:

它们是安托西安氨酸.蓝蓝蓝是一种聚醇是一种多醇.精准营养精准营养精准营养

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