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无痛毛细血管血液采集:对上流装置的快速评估
Lara Dominique Noble1, Caitlin Dixon1, Alison Moran2
1WITS Diagnostic Innovation Hub, University of the Witwatersrand, Johannesburg 2000, South Africa.
Diagnostics (Basel, Switzerland)
|May 27, 2023
概括
在Onflow血清凝设备提供了一个无针,用户友好的替代收集血液,显示高参与者接受和最小的临床影响关键化学分析物,尽管轻微的血液溶解.
科学领域:
- 医学诊断 医学诊断 医学诊断
- 生物技术是生物技术.
- 临床化学 临床化学
背景情况:
- 血液采集用于诊断往往涉及静脉穿刺,这可能会引起疼痛和不便.
- 新型采血设备旨在改善患者体验和可访问性.
研究的目的:
- 评估Onflow血清凝无针采血装置的可接受性,可用性和分析性能.
- 为了比较Onflow收集的血液样本与传统的风口穿刺样本,以获得关键化学分析物.
主要方法:
- 一项试点研究涉及100名健康参与者.
- 收集两个Onflow毛细血管血液样本和每个参与者的一个静脉穿刺样本.
- 在所有样本中测量了五种化学分析物 (AST,ALT,LDH,,肌) 和血液溶解.
主要成果:
- 与静脉穿刺相比,Onflow显示了更高的参与者接受度和更低的疼痛评级.
- 弗莱博托米学家发现Onflow设备直观且易于使用.
- 对ALT和AST的分析结果显示没有差异;肌素表现出负偏差,和LDH显示变异性增加,尽管不具有临床意义.
- 在35%的Onflow标本中观察到轻度血液溶解,这可能解释了分析物变异性.
结论:
- 在Onflow血清凝设备是一个有前途的,可接受的,和用户友好的无针替代采集血液.
- 在异常化学成分的患者群体和自我收集应用中,需要进一步评估.
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