儿科COVID-TB:基于对三例病例分析的临床观点
Fabrizio Leone1, Martina Di Giuseppe2, Maia De Luca2
1Maternal, Infantile and Urological Sciences Department, Sapienza University of Rome, 00161 Rome, Italy.
Children (Basel, Switzerland)
|May 27, 2023
概括
在儿童中与结核病 (TB) 和2019年冠状病毒病 (COVID-19) 共同感染,称为COVID-TB,是罕见的. 这份报告详细介绍了三个儿科病例,强调了在这些共感染患者中需要谨慎管理和观察.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 呼吸系统医学 呼吸系统医学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 和结核病 (TB) 是全球重要的健康威胁.
- 与COVID-19和结核病的同时感染,称为COVID-TB,已在成年人中观察到,但很少在儿童中描述.
- 结核病与严重的COVID-19结果的风险增加有关.
研究的目的:
- 描述了三例儿童肺结核和SARS-CoV-2联合感染的病例.
- 突出COVID-TB在儿童中的临床表现和管理.
- 强调儿童COVID-TB病例的潜在风险和需要仔细观察的需要.
主要方法:
- 病例系列报告了三名被诊断患有结核病和SARS-CoV-2感染的儿科患者.
- 分析了包括患者病史,症状,诊断结果和治疗过程在内的临床数据.
- 对成年COVID-TB病例进行文学综述,以进行比较和风险评估.
主要成果:
- 三个以前健康的5岁,10岁和13岁的女孩呈现出不同形式的结核病 (淋巴腺病,肺,,扩散性).
- 所有患者的SARS-CoV-2检测结果都呈阳性.
- 虽然一个患者没有COVID-19并发症,另一个患者需要治疗两种情况,第三个患者在没有COVID-19并发症的情况下传播了结核病.
结论:
- 儿科COVID-TB共感染,虽然很少见,但可能会发生,并可能带来更糟糕的临床结果的风险.
- 建议对COVID-TB的儿科患者进行密切的临床观察,仔细管理,并考虑针对性抗SARS-CoV-2疗法.
- 需要进一步的研究来了解COVID-TB对儿童的全面影响和最佳治疗策略.
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