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在接受肥胖手术的患者中,功能障碍的表型
Pedro R Pereira1,2,3, João Pereira2,3, Patrícia C Braga2,3
1Department of Nephrology, Centro Hospitalar de Trás-os-Montes e Alto Douro (CHTMAD), 5000-508 Vila Real, Portugal.
Biomolecules
|May 27, 2023
概括
肥胖手术候选人经常患有功能障碍,包括白蛋白尿和蛋白尿,以及过. 对于这些患者,建议进行常规的手术前功能评估.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 腹部外科 腹部外科
- 腎臟健康 腎臟健康
背景情况:
- 肥胖手术候选人面临损伤风险的增加.
- 手术前的功能评估经常被忽视.
- 了解这群人群中的功能障碍对于患者的安全至关重要.
研究的目的:
- 在寻求减肥手术的个人中识别功能障碍.
- 为了调查蛋白尿,白蛋白尿和过的患病率.
- 为了确定与这种队列中的功能障碍相关的因素.
主要方法:
- 这项研究包括了192名减肥手术候选人 (BMI为41.7±5.4 kg/m2).
- 排除了患有糖尿病,接受甲福林治疗的糖尿病前期,瘤或炎症性疾病的患者.
- 评估了肌素清除,蛋白尿,白蛋白尿,糖化血红蛋白和脂质概况.
主要成果:
- 51%的人表现出肌素清除率>140毫升/分钟 (过).
- 22.4%的蛋白尿 >150毫克/天;14.6%的蛋白尿 >30毫克/天.
- 白蛋白尿与更高的糖化血红蛋白和肌素清除有关;蛋白尿没有.
结论:
- 糖尿病前期,脂质问题和高尿血与肥胖手术候选人的白色素尿相关.
- 在与肥胖相关的脏疾病中,管间伤害可能会先于淋巴细胞病变.
- 建议在这些候选人中进行常规查白蛋白尿和蛋白尿.
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