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Updated: Jul 29, 2025

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mef2ca和mef2cb双变异斑马鱼显示了改变的面表型和运动行为

Andreia Adrião1, Sara Mariano1, José Mariano2,3

  • 1Centre of Marine Sciences (CCMAR), Universidade do Algarve, Campus de Gambelas, 8005-139 Faro, Portugal.

Biomolecules
|May 27, 2023
PubMed
概括

斑马鱼MEF2C基因突变体现出严重的面和心脏缺陷,以及行为变化,反映了人类MRD20疾病. 这证实了它们作为疾病研究和治疗开发模型的实用性.

关键词:
在MEF2C的Haploinsufficiency综合征中.Mef2c突变物种的突变物种肌细胞增强因子2 (MEF2C)自体主导性精神衰退综合征-20 疾病 (MRD20)头骨面部的发展.斑马鱼 (Danio rerio) 是一种鱼类.

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