神经疾病的动物模型:我们现在在哪里?
1Department of Psychiatry, School of Clinical Sciences, Monash University, Clayton, VIC 3168, Australia.
Biomedicines
|May 27, 2023
概括
动物模型对于理解神经系统疾病至关重要. 本专期回顾了该领域的当前进展和未来方向.
科学领域:
- 神经科学和生物医学研究.
- 比较医学和病理学.
背景情况:
- 对目前神经系统疾病的动物模型进行全面的审查.
- 评估现有模型的翻译有效性.
- 识别当前动物模型研究中的差距.
相关概念视频
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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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