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Updated: Jul 29, 2025

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通过KinetiSol将聚合物混合物预处理成聚合物合金,可以增加Ivacaftor无形固体分散药物加载和溶解

Stephen A Thompson1, Daniel A Davis2, Dave A Miller2

  • 1Molecular Pharmaceutics and Drug Delivery Division, College of Pharmacy, The University of Texas at Austin, 2409 W. University Ave, PHR 4.214, Austin, TX 78712, USA.

Biomedicines
|May 27, 2023
PubMed
概括

在无形固体分散 (ASD) 配方之前创建聚合物合金可以增强药物加载和溶解. 与传统混合物相比,将聚合物预加工成单相合金提高了 ivacaftor ASD 的性能.

关键词:
卡利德可可是一种酸盐.无形固体分散的无形固体分散溶解溶解是一种毒品装载 毒品装载通过联结,形成联结.伊瓦卡夫托尔 (Ivacaftor) 是一个一个聚合物聚合物.聚合物合金的聚合物合金.溶解度 溶解度 溶解度 溶解度

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