儿科患者的SARS-CoV-2抗体反应:一个图书识别分析
Ionela Maniu1,2, George Constantin Maniu1, Elisabeta Antonescu3,4
1Mathematics and Informatics Department, Research Center in Informatics and Information Technology, Faculty of Sciences, "Lucian Blaga" University, 5-7 Ion Ratiu Str., 550025 Sibiu, Romania.
Biomedicines
|May 27, 2023
概括
本文献统计综述分析了儿科SARS-CoV-2抗体反应,总结了关于抗体标位及其与免疫标志物相关性的关键发现. 该研究强调了国际研究合作和未来理解儿科COVID-19免疫力的方向.
科学领域:
- 免疫学 免疫学 免疫学
- 病毒学 病毒学
- 图书统计学 图书统计学
背景情况:
- 儿童对SARS-CoV-2的免疫反应仍然不完全理解.
- 评估抗体动态对于理解儿科COVID-19至关重要.
- 图书统计分析提供了对研究趋势的全面概述.
研究的目的:
- 进行对儿科人口中SARS-CoV-2抗体反应研究的文献统计审查.
- 总结针对各种SARS-CoV-2抗原的抗体标位的发现.
- 探索儿童抗体和其他免疫标记物之间的相关性.
主要方法:
- 来自Web of Science的84个出版物的图书统计审查.
- 使用VOSviewer和Bibliometrix软件进行分析.
- 包括评估SARS-CoV-2抗体标位和相关免疫标记物的研究.
主要成果:
- 在29个国家的310个机构中确定了全球研究合作.
- 对各种SARS-CoV-2抗原 (N,RBD,Spike变种) 的总结抗体标位 (IgG,IgM,IgA).
- 详细的SARS-CoV-2抗体与细胞因子,化学因子,中性粒细胞,CRP,费里丁和ESR之间的相关性.
结论:
- 该审查强调了儿童COVID-19研究中的重大国际科学合作.
- 结果提供了对抗体反应及其与儿童免疫因素的关联的综合观点.
- 这项研究作为未来对儿科SARS-CoV-2免疫力的研究的基础.
相关概念视频
01:05Single Nucleotide Polymorphisms-SNPs
15.3K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
15.3K
02:50Conjugated Proteins
18.4K
Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
18.4K
01:03Rous Sarcoma Virus (RSV) and Cancer
5.2K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
5.2K