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Updated: Jul 29, 2025

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在膝关节骨关节炎中,流体血管断裂

Madhan Jeyaraman1,2,3, Nicola Maffulli4,5,6,7, Ashim Gupta3,8,9,10

  • 1Department of Orthopaedics, ACS Medical College and Hospital, Dr. MGR Educational and Research Institute, Chennai 600056, Tamil Nadu, India.

Biomedicines
|May 27, 2023
PubMed
概括

骨关节炎 (OA) 影响了3000万美国人,造成了严重的残疾和经济压力. 这种情况严重影响了受影响者的生活质量.

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
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