第一代和第二代情绪稳定剂
1Department of Adult Psychiatry, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Brain sciences
|May 27, 2023
概括
本综述详细介绍了情绪稳定剂,根据其在治疗双相情绪障碍方面的引入和有效性,将其分为第一代 (例如,) 和第二代 (例如,非典型抗精神病药物).
科学领域:
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 情绪稳定剂对于治疗双相情绪障碍至关重要.
- 分类情绪稳定剂有助于理解它们的治疗进化.
研究的目的:
- 定义和描述情绪稳定药物.
- 将情绪稳定剂根据其引入和特性分为几代.
- 审查临床经验和当前关于在双相情绪障碍中使用情绪稳定剂的建议.
主要方法:
- 情绪稳定剂的叙事审查.
- 情绪稳定剂的分类:第一代和第二代.
- 药物的描述包括,瓦尔酸盐,卡巴马西平,非典型抗精神病药物和拉莫特里金.
主要成果:
- 第一代情绪稳定剂 (FGMSs) 包括,酸和卡巴马泽平 (1960年代-1970年代).
- 从1995年开始,第二代情绪稳定剂 (SGMSs) 包括非典型的抗精神病药物 (克洛扎宾,奥兰扎宾,奎蒂亚平,阿里皮拉,RISPERIDONE) 和拉莫特里金.
- 一些药物显示出潜力,但并不完全符合作者对情绪稳定剂的标准.
结论:
- 情绪稳定剂被分为两代,具有不同的药理学特征.
- 了解这些分类是有效治疗双相情绪障碍和预防情绪复发的关键.
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