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使用扩散张力成像对2型糖尿病外围神经病变患者的腰部神经根的评估

He Chen¹, Yanyan Xu², Wei Wang³

¹Department of Radiology, Peking University China-Japan Friendship School of Clinical Medicine, Yinghua Street 2, Chaoyang District, Beijing 100029, China.

|May 27, 2023

概括

扩散张力成像 (DTI) 可以通过分析腰部神经根来检测糖尿病外围神经病变 (DPN). 这种先进的MRI技术对诊断DPN和理解神经损伤充满希望.

科学领域:

神经成像是一种神经成像.
放射学放射学是指放射学
医学诊断医学诊断医学诊断

背景情况:

扩散张力成像 (DTI) 是为中央神经系统和外围神经病变的评估而建立的.
有限的研究存在于糖尿病外围神经病变 (DPN) 中 lumbosacral 神经根纤维损伤.

研究的目的:

通过检查 lumbosacral 神经根来评估 DTI 在检测 DPN 的实用性.
为了评估DTI对DPN的诊断准确性.

主要方法:

在32名DPN患者和30名对照群中,使用DTI和L4,L5,S1神经根的三次磁力共振成像和通道图.
测量分数异构性 (FA) 和明显扩散系数 (ADC) 的值.
与临床数据和神经传导研究 (NCS) 的相关性分析.

主要成果:

与对照组相比,DPN患者的FA降低 (p < 0.001),ADC增加 (p < 0.001).与对照组相比,DPN患者的FA降低 (p < 0.001),ADC增加 (p < 0.001).
FA获得了最高的诊断准确性 (AUC = 0.716).
在DPN组中,ADC与HbA1c水平 (r = 0.379,p = 0.024) 呈正相关性.

结论:

腰部神经根的DTI为DPN提供了重要的诊断价值.
这些发现支持DTI作为确定糖尿病患者神经根损伤的可行工具.

关键词:

糖尿病周围神经病变扩散张力成像的成像方法腰部神经根腰部神经根磁共振成像技术的使用路径学路径学路径学路径学路径学

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