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Updated: Jul 29, 2025

Establishment of an Electrophysiological Platform for Modeling ALS with Regionally-Specific Human Pluripotent Stem Cell-Derived Astrocytes and Neurons
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Published on: August 26, 2021

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创建一个开放访问的患者衍生的iPSC生物库,用于模拟肌缩侧面硬化症疾病

Erin C Hedges1, Graham Cocks2, Christopher E Shaw1,3

  • 1United Kingdom Dementia Research Institute, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 5 Cutcombe Rd., London SE5 9RT, UK.

Genes
|May 27, 2023
PubMed
概括

研究人员创建了一个来自基因突变患者的性多能干细胞 (iPSC) 生物库. 这些iPSC系列模拟了早期的ALS表型,有助于治疗的发展.

关键词:
骨髓缩侧面硬化症 (ALS) 是一种生物银行生物银行疾病建模 疾病建模诱导的多能干细胞干细胞.

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