皮肤冠状动脉干预在老年风湿关节炎患者的结果:全国性基于人口的队列研究
Bo Young Kim1, HyeSung Moon2, Sung-Soo Kim1
1Division of Rheumatology, Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung 25440, Republic of Korea.
Healthcare (Basel, Switzerland)
|May 27, 2023
概括
经过皮肤冠状动脉干预 (PCI) 的风湿性关节炎 (RA) 的老年患者面临更高的死亡风险. 在PCI后,年轻发病的RA患者的生存率比老年发病的RA患者要好.
科学领域:
- 心脏病学 心脏病学
- 类风湿病学 类风湿病学
- 老年病的医生 老年病的医生
背景情况:
- 类风湿性关节炎 (RA) 是心血管疾病的重要危险因素.
- 在老年人群中,了解RA对穿皮冠状动脉干预 (PCI) 后的结果的影响至关重要.
研究的目的:
- 评估和比较经皮冠状动脉干预 (PCI) 后的风湿性关节炎 (RA) 和没有风湿性关节炎 (RA) 的老年患者的临床结果,特别是生存率.
主要方法:
- 使用韩国国家医疗保险服务索赔数据库,对74,623名老年患者 (≥65岁) 进行了回顾性分析,这些患者在2008-2019年期间接受了急性冠状动脉综合征的PCI.
- 在RA患者 (n=14,074) 和没有RA患者 (n=60,549) 之间的所有原因死亡率的比较.
- 基于RA发病年龄 (年轻发病与老年发病) 的生存结果的子组分析.
主要成果:
- 在10年的随访期间,RA患者的老年患者的生存率与没有RA患者相比显著较低 (53.7%对58.3%,p < 0.001).
- 在RA小组中,患有年轻发病的RA的患者比患有老年发病的RA和没有RA的患者有更好的生存结果 (73.7%对48.1%对58.3%,p < 0.001).
- 接受PCI的老年RA患者经历了较高的死亡风险,特别是那些老年发病的RA患者.
结论:
- 接受PCI的风湿性关节炎老年患者死亡风险增加.
- RA 发病的年龄显著影响PCI后老年患者的生存结果,年轻发病的 RA 与老年发病的 RA 相比,预后更好.
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