慢性腰部疼痛和事件 暂时性缺血性发作和中风 在德国的全科医院
Louis Jacob1,2,3, Lee Smith4, Ai Koyanagi1,5
1Research and Development Unit, Parc Sanitari Sant Joan de Déu, CIBERSAM, ISCIII, Dr. Antoni Pujadas, 42, 08830 Barcelona, Spain.
Healthcare (Basel, Switzerland)
|May 27, 2023
概括
慢性腰部疼痛 (CLBP) 与患过渡性缺血性发作 (TIA) 和中风的风险更高有关. 这项德国研究发现了显著的关联,强调了进一步调查这一联系的必要性.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 慢性腰部疼痛 (CLBP) 是一种普遍存在的疾病,具有潜在的全身影响.
- 了解CLBP和脑血管事件之间的关联对于患者管理至关重要.
研究的目的:
- 调查慢性腰部疼痛 (CLBP) 与德国人口中暂时性缺血性发作 (TIA) 和中风的发生率之间的联系.
- 量化患有CLBP的人与不患有CLBP的人之间的TIA或中风风险.
主要方法:
- 这是一项追溯性队列研究,涉及德国159,440名成年人 (2005-2019).
- 倾向性得分匹配 (1:1) 用于比较患有和没有CLBP的患者.
- 随访期长达10年,以确定发生的TIA或中风诊断.
主要成果:
- 在10年内,与没有 (5.9%) 患者相比,患有CLBP的患者 (6.5%) 观察到TIA或中风的发生率显著更高 (日志排名p < 0.001).
- 考克斯回归分析显示,CLBP和发生的TIA或中风之间存在显著的关联 (HR = 1.28,95% CI = 1.22-1.35).
结论:
- 慢性腰部疼痛与德国发生TIA和中风的风险增加有积极和显著的关联.
- 需要进一步的研究来阐明连接CLBP和脑血管事件的潜在机制.
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