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Updated: Jul 29, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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1H-英达-3-胺衍生物的设计,合成和抗瘤活性

Congyu Wang1,2, Mei Zhu3, Xuesha Long1,2

  • 1College of Pharmacy, Guizhou University, Guiyang 550025, China.

International journal of molecular sciences
|May 27, 2023
PubMed
概括

研究人员开发了新的因达衍生物作为潜在的抗癌剂. 化合物6o对慢性髓性白血病 (K562) 细胞进行了强有力的和选择性的抑制,这表明它对癌症治疗有前途.

关键词:
它具有抗瘤活性.细胞亡是细胞的亡.在达醇衍生物中.p53/MDM2 路径的使用.

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