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突变驱动的S100A8过度表达在1型CALR-突变的MPN中产生异常的表型

Ying-Hsuan Wang1, Ying-Ju Chen1, Yi-Hua Lai1

  • 1Division of Hematology and Oncology, Department of Medicine, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan.

International journal of molecular sciences
|May 27, 2023
PubMed
概括

骨髓增殖性新生瘤 (MPN) 中不同的卡尔雷蒂库林 (CALR) 突变导致S100A8表达的变化,影响疾病表型. CALR外因子9删除 (CALRDEL) 独特地增加S100A8,影响细胞增殖和细胞亡.

关键词:
在S100A8A8中使用.卡尔雷蒂库林是一种卡尔雷蒂库林.骨髓扩散性瘤是什么现象型 现象型 是一种现象型.促进剂低甲基化 促进剂低甲基化一种类型1 CALR突变

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