成年患者的血栓栓塞并发症在Fontan程序后-一个多中心研究
Maciej Skubera1, Aleksandra Gołąb2,3, Tomasz Sternalski4
1Department of Cardiac and Vascular Diseases, John Paul II Hospital, 31-202 Krakow, Poland.
Journal of clinical medicine
|May 27, 2023
概括
在Fontan (FO) 手术后,成年人经常出现血栓栓塞并发症 (TEC),通常发生在年轻人中. 这些事件,包括肺栓塞,被低估,需要进一步研究标准化的预防策略.
科学领域:
- 心脏病学 心脏病学
- 成年人的先天性心脏病
- 血栓塞栓症 血栓塞栓症 血栓塞栓症
背景情况:
- 在Fontan (FO) 手术后的发病率和死亡率与血栓栓塞并发症 (TEC) 有关.
- 成年Fontan患者TEC的随访数据不一致.
- 这项研究调查了成年Fontan患者的TEC发病率.
研究的目的:
- 为了确定Fontan (FO) 程序后成年患者中血栓栓塞并发症 (TEC) 的发生率.
- 分析这一群体中TEC的特征和时间.
- 为了突出越来越多的成年FO人群中低估了TEC的情况.
主要方法:
- 在91名接受Fontan (FO) 手术的患者中进行了前性多中心研究.
- 从波兰的3个成人先天性心脏病部门收集的数据.
- 平均随访时间为31个月,记录血栓栓塞并发症 (TEC).
主要成果:
- 23.1%的患者在FO手术后有24次TEC (主要是肺栓塞,PE) 的病史.
- 在随访期间,8.0%的患者经历了9次新的TEC (主要是PE).
- 大多数TEC发生在左侧全身心室患者中;抗血栓治疗有所不同.
结论:
- 血栓塞栓并发症 (TECs) 在成年Fontan (FO) 患者中很常见.
- 显著比例的TEC发生在青春期和年轻成年期.
- 在Fontan人群中标准化的TEC预防需要进一步调查.
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