在SARS-CoV2感染后患者的格林林和丁度
Justyna Kuliczkowska-Płaksej1, Aleksandra Jawiarczyk-Przybyłowska1, Agnieszka Zembska1
1Department and Clinic of Endocrinology, Diabetes and Isotope Therapy, Wrocław Medical University, Wybrzeże Pasteura 4, 50-367 Wroclaw, Poland.
Journal of clinical medicine
|May 27, 2023
概括
在SARS-CoV-2感染六个月后,格林水平更高,特别是在女性中. 这项研究调查了COVID-19患者的阿迪波金失调,发现格林蛋白度发生了变化,但没有发现叶丁度.
科学领域:
- 内分泌学 在内分泌学.
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
背景情况:
- SARS-CoV-2 感染可以引发严重的细胞因子风暴,特别是在肥胖个体中.
- 格林和瘦素等阿迪波基因在食欲调节和免疫反应中起作用.
- 与肥胖相关的阿迪波金失调可能会导致COVID-19的严重程度.
研究的目的:
- 在SARS-CoV-2感染后6个月的患者中评估格林和丁度.
- 将这些水平与健康的对照组进行比较.
- 为了研究性别对这些阿迪波金水平的影响.
主要方法:
- 研究包括53名COVID-19幸存者和87名健康对照.
- 测量了血清格林和瘦素度.
- 评估了荷尔蒙和生化参数,包括和皮质醇.
主要成果:
- 与对照组相比,在COVID-19组中发现了显著更高的格林度.
- 性别显著影响了COVID-19和格林的关系,男性的水平较低.
- 两组之间没有观察到丁度的显著差异.
- 格林在COVID-19患者中与丸激素和早晨皮质醇呈负相关性.
结论:
- 在轻度SARS-CoV-2感染6个月后,格林林水平仍然升高.
- 需要进一步的研究来比较轻度与严重的COVID-19疗程中的ghrelin水平.
- 在康复的COVID-19患者和对照人群中,丁度没有差异.
相关概念视频
Regulation of Food Intake
290
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
290
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
127
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
127
Hypoglycemia and Glucagon
306
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
306


