长期COVID和COVID再感染中的化学感知感知特征
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Mikki Jaramillo1, Thankam P Thyvalikakath2, George Eckert3
1Department of Oral Pathology, Medicine and Radiology, Indiana University School of Dentistry, Indiana University Purdue University at Indianapolis, Indianapolis, IN 46202, USA.
Journal of clinical medicine
|May 27, 2023
概括
冠状病毒疾病-19 (COVID-19) 后,改变口味和气味等持续症状很常见,影响长期COVID和COVID再感染患者. 女性经历了较长时间的COVID和再感染的更高负担,感官功能障碍持续了多年.
科学领域:
- 传染性疾病 传染性疾病
- 神经学 神经学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 新出现的数据表明,COVID-19后持续症状的发病率正在上升.
- 化学感官功能障碍,包括味觉和嗅觉的改变,是经常报告的COVID后症状.
研究的目的:
- 调查长期COVID患者和COVID再感染患者的味道和气味变化的比较频率.
- 为了确定这两个患者群体之间的人口和症状差异.
主要方法:
- 在印第安纳大学健康COVID注册表中,向225名患者分发了一份电子调查.
- 该调查查询了与长期COVID相一致的症状,包括化学感官变化,并区分了单次 (长期COVID) 和多次 (再感染) 阳性COVID-19测试.
主要成果:
- 妇女的长期COVID和COVID再感染的患病率更高.
- 关节疼痛是长期COVID队列中最常见的症状 (18%). 头痛,关节疼痛和咳在COVID再感染队列中报告了20%以上.
- 与长期COVID队列相比,在COVID再感染队列中观察到明显更高的味觉 (42%) 和嗅觉 (46%) 的恶化率 (29%的味觉,37%的嗅觉).
- 在两个队伍中,在COVID前的味道/气味严重程度和头痛之间发现了显著的关联.
结论:
- 持续的化学感官功能障碍在长期COVID和COVID再感染中普遍存在,持续两年或更长时间.
- 与长期COVID相比,COVID再感染可能与更高频率的味觉和嗅觉障碍有关.
- 头痛可能与先前存在的味道和气味感知严重程度有关.
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