人类产前大脑发育的神经形态图集:白皮书
Alexandra Proshchina1, Anastasia Kharlamova1, Yuliya Krivova1
1Avtsyn Research Institute of Human Morphology of Federal State Budgetary Scientific Institution "Petrovsky National Research Centre of Surgery", Tsurupi Street, 3, 117418 Moscow, Russia.
Life (Basel, Switzerland)
|May 27, 2023
概括
人类产前大脑发育图谱 (HBDA) 提供了关于人类大脑发育的初步数据,为研究提供注释地图和免疫类型特征. 此资源有助于神经学研究和对大脑发育病理学的理解.
科学领域:
- 神经科学是一个神经科学.
- 发展生物学 发展生物学
- 医疗成像医学成像
背景情况:
- 人类大脑发育的形态学数据目前有限.
- 这些数据对于医疗实践,教育和跨多个科学学科的基础研究至关重要.
研究的目的:
- 介绍人类产前大脑发育图谱 (HBDA),一个新的在线资源.
- 提供关于产前人类大脑发育的详细的时空信息.
主要方法:
- 开发一个在线地图集,包括人类胎儿前脑的注释半球地图.
- 使用来自各种产前发育阶段的序列截图.
- 在虚拟序列段上展示区域特定的免疫类型特征.
主要成果:
- HBDA最初包括前脑半球在产前阶段的注释地图.
- 它展示了区域免疫类型特征的时空变化.
- 可以通过HBDA网站访问初步数据.
结论:
- 该HBDA作为神经学研究的一个有价值的参考数据库.
- 它有助于与非侵入性成像和空间转录学数据进行比较.
- 这本地图书支持对个体大脑变异性的分析和研究神经发生机制,用于治疗开发.
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