口腔健康和疾病中的精准医学:系统性审查
Giuseppina Malcangi1, Assunta Patano1, Mariafrancesca Guglielmo1
1Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", 70121 Bari, Italy.
Journal of personalized medicine
|May 27, 2023
概括
精准医学 (PM) 通过将"omics"数据集成到预测模型中来提供个性化疗法. 精密牙科 (DP) 应用这些进步来改善治疗计划,诊断和患者的治疗结果.
科学领域:
- 基因组学和生物信息学
- 个性化医疗是个性化的医疗.
- 牙科科学 牙科科学
背景情况:
- 精准医学 (PM) 通过个性化疗法彻底改变了医疗保健.
- 奥米克科学集成数据用于预测生物模型.
- 精密牙科 (DP) 是一个新兴的应用,需要进一步探索.
研究的目的:
- 为医生提供牙科准确医学的概述.
- 提高对治疗计划和患者反应的理解.
- 突出PM在各种牙科领域的潜力.
主要方法:
- 系统的文献审查.
- 对PubMed,Scopus和Web of Science的文章进行分析.
- 检查精准医学在牙科中的作用.
主要成果:
- PM有助于预防癌症,识别风险因素,并管理像 orofacial 裂这样的形.
- 用于治疗疼痛的药物重用针对特定的生物化学机制.
- 基因组研究揭示了细菌殖民和炎症的遗传性,有利于皮和牙周炎的管理.
- 在正牙科和再生牙科方面,PM显得有前途.
结论:
- 精准医学为改善牙科诊断,治疗和预防提供了巨大的潜力.
- 整合omics数据和促进国际数据库可以带来更好的疾病管理和成本节省.
- 对精密牙科的进一步研究对于实现其全部好处至关重要.
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