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Assessment of Vascular Function in Patients With Chronic Kidney Disease
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胃食道逆流性疾病与慢性病之间的关系
Xiaoliang Wang1, Zachary Wright2, Eva D Patton-Tackett1
1Internal Medicine Residency Program, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV 25701, USA.
Journal of personalized medicine
|May 27, 2023
概括
慢性病 (CKD) 与胃食道逆流性疾病 (GERD) 的更高患病率有关. 慢性病患者的GERD和其并发症 (如食道狭窄和巴雷特食道) 的几率增加.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 胃食道逆流病 (GERD) 经常在患有慢性病 (CKD) 的患者中观察到.
- 关于GERD及其并发症在CKD患者中的特定关系和患病率的数据有限.
研究的目的:
- 调查慢性病 (CKD) 与胃食道逆流性疾病 (GERD) 的患病率之间的联系.
- 探索CKD与GERD相关并发症的发生之间的关系,例如巴雷特食道和食道狭窄.
主要方法:
- 对来自7,159,694名患者的全国住院样本数据的回顾性分析.
- 在CKD和无CKD患者之间比较GERD患病率和并发症,并根据风险因素进行调整.
- 评估CKD不同阶段与GERD及其并发症的关系,使用双变量分析.
主要成果:
- 在CKD患者 (23.5%) 中,与非CKD患者 (14.8%) 相比,GERD的患病率明显更高.
- 慢性病患者的经调整后患有GERD的概率高出1.7%,这一趋势在所有慢性病阶段均一致.
- 患有早期CKD的患者与非CKD患者相比,食道狭窄和巴雷特食道的患病率和概率更高.
结论:
- 慢性病与胃食道逆流性疾病的更高患病率显著相关.
- 慢性脏病与GERD并发症的风险增加有关,包括食道狭窄和巴雷特食道.
- 这些发现凸显了CKD和GERD之间重要的共患性,需要进一步的临床关注.
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