伴随性疾病概况和阻塞性睡眠呼吸暂停的预测因素,非肥胖阻塞性睡眠呼吸暂停患者的严重程度和死亡率
Dragana Milicic Ivanovski1, Branka Milicic Stanic1,2, Ivan Kopitovic1,3
1Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.
Medicina (Kaunas, Lithuania)
|May 27, 2023
概括
阻塞性睡眠呼吸暂停 (OSA) 与更高的心血管疾病风险和死亡率有关. 这项研究发现,非肥胖OSA患者心血管和死亡风险增加,与OSA严重程度相关.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 睡眠医学 睡眠医学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是心血管疾病,发病率和死亡率的重要危险因素.
- 了解非肥胖OSA患者的并发症概况和风险分层对于有效管理至关重要.
研究的目的:
- 为了确定新诊断的OSA的非肥胖患者的并发症概况.
- 评估这些患者心血管疾病和死亡的10年风险.
- 为了确定OSA严重程度的预测因素.
主要方法:
- 138名新诊断的OSA患者接受了多睡眠学.
- 使用系统冠状动脉风险评估 (SCORE-2) 模型评估心血管风险.
- 使用查尔森并发症指数 (CCI) 评估的死亡风险.
主要成果:
- 心血管风险 (SCORE-2) 和并发症负担 (CCI) 随着OSA的严重程度显著增加.
- 与对照组相比,OSA患者表现出更高的心血管风险和并发病率.
- 在OSA患者中观察到较低的10年生存率 (CCI),特别是那些患有严重OSA患者.
结论:
- 并发症概况和风险评分估计有助于将OSA患者分类为死亡风险类别.
- 根据个体风险分层,可以制定定制的治疗策略.
- 早期识别和管理OSA并发症对于改善患者的治疗结果至关重要.
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