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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

使用扫描源光学一致性断层扫描对眼径参数的评估.

Jing Dong¹, Jinhan Yao², Shuimiao Chang²

¹Department of Ophthalmology, First Hospital of Shanxi Medical University, Taiyuan 030001, China.

Medicina (Kaunas, Lithuania)

|May 27, 2023

概括

虹膜角对角 (ATA) 和阴道对阴道 (STS) 的直径垂直比水平更长,与白对白 (WTW) 测量不同. 这些发现提高了可植入合镜 (ICL) 和前腔内眼镜 (ACIOL) 的尺寸精度.

关键词:

这是一个角度对角度的角度.前腔室眼内镜片眼内镜片的前腔室可植入的拼接镜头镜头.脊髓刺激到脊髓刺激扫描源光学连贯性断层扫描仪从白色到白色的白色.

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科学领域:

眼科医生眼科眼科
光学连贯性断层扫描技术
生物识别仪表是如何使用的

背景情况:

准确的眼内镜片 (IOL) 尺寸对于最佳的折射结果至关重要.
现有的生物识别测量,如白色对白色 (WTW),可能无法完全捕捉前段解剖学用于IOL计算.
中国人群可能具有独特的眼睛尺寸,影响IOL选择.

研究的目的:

为了比较虹膜角与角 (ATA),膜刺激与膜刺激 (STS) 和白色与白色 (WTW) 的眼径.
为了评估这些直径对前腔眼内透镜 (ACIOL) 和可植入眼内透镜 (ICL) 尺寸的影响.
通过扫描源光学连贯性断层扫描 (SS-OCT) 对中国受试者的这些测量进行评估.

主要方法:

60名中国受试者的回顾性,观察性,横截面研究.
在六个轴上使用SS-OCT测量ATA,STS和WTW.
基于前段数据计算ACIOL和ICL大小;统计分析包括配对t测试和皮尔森相关性.

主要成果:

与水平轴相比,ATA和STS在垂直轴上显著更长,而WTW测量在轴之间相似.
ATA和STS在垂直轴上比WTW更宽.
基于水平与垂直轴参数的ICL尺寸计算显示出显著的差异,与ACIOL不同;年龄和轴长与所有测量直径显示出显著的相关性.

结论:

与WTW测量相比,ATA和STS直径提供了更准确的眼睛解剖学表示,用于 phakic IOL大小测量.
垂直ATA和STS测量对于精确的ICL和ACIOL测量至关重要,特别是在中国人群中.
SS-OCT是详细的前段生物识别的宝贵工具,有助于个性化的IOL选择.