诊断和个性化治疗宫癌的挑战
Melanie Schubert1, Dirk Olaf Bauerschlag1, Mustafa Zelal Muallem2
1Department of Obstetrics and Gynecology, University Hospital of Schleswig Holstein, Campus Kiel, 24105 Kiel, Germany.
Medicina (Kaunas, Lithuania)
|May 27, 2023
概括
宫癌仍然是一个全球性的健康挑战,预防和治疗的进展在全球范围内有很大的差异. 本综述强调了最近在宫癌诊断和管理方面的进展,重点关注全球趋势和德国创新.
科学领域:
- 在瘤学瘤学.
- 妇科 妇科 妇科 妇科
- 公共卫生 公共卫生
背景情况:
- 宫癌是全球女性第四常见的癌症,在2020年有604,000例新病例.
- 虽然工业化国家由于HPV疫苗接种和早期检测而减少了发病率,但全球死亡率和发病率仍然很高.
- 对病原体的理解得到了改善,使得个性化治疗策略成为可能.
研究的目的:
- 审查最近在宫癌预防,诊断和治疗方面的全球进展.
- 专注于德国取得的具体进展.
- 为临床医生提供关于宫癌管理的最新概述.
主要方法:
- 综合文献综述,重点关注最近的进展.
- 诊断工具的分析,包括成像,细胞学和病理学.
- 检查各种治疗方式:药物,手术等.
主要成果:
- 讨论了宫癌的患病率,原因和病理机制.
- 详细介绍当前的诊断能力及其有效性.
- 比较不同治疗结果及其影响.
结论:
- 在全球范围内,宫癌的结果存在显著差异.
- 持续的研究和先进战略的实施对于减少全球负担至关重要.
- 专注于德国提供了对宫癌控制有效医疗保健系统整合的见解.
相关概念视频
Combination Therapies and Personalized Medicine
5.0K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.0K
Cancer Therapies
7.8K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.8K
Cancer
48.8K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
48.8K
Cancer Vaccines
437
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
437
Targeted Cancer Therapies
7.7K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.7K
Tumor Immunotherapy
577
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
577


