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在中度COVID-19感染的住院儿童中轻度高糖血症
Jarmila Vojtková1, Peter Bánovčin1, Anna Ďurdíková1
1Department of Paediatrics, Comenius University in Bratislava, Jessenius Faculty of Medicine and University Hospital, 036 01 Martin, Slovakia.
与其他病毒感染相比,中度COVID-19感染的儿童患高血糖率更高. 当COVID-19出现发烧或胃肠道症状时,这种联系特别强烈.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 内分泌学 在内分泌学.
背景情况:
- COVID-19 感染可以影响生理过程,包括葡萄糖代谢.
- 急性高血糖症与严重的COVID-19病例中较差的结果有关.
- 中度COVID-19和高血糖之间的关系需要进一步调查.
研究的目的:
- 为了确定中度的COVID-19感染是否与儿童的高血糖相关.
- 为了比较COVID-19儿童的高血糖率与其他RNA病毒感染.
主要方法:
- 研究了235名儿童 (112名患有COVID-19,123名患有其他RNA病毒感染) 的队列.
- 收集的数据包括症状,入院血糖和生物化学参数.
- 统计分析比较了不同组的血糖水平和高血糖风险.
主要成果:
- COVID-19患者的平均血糖 (5.7 ± 1.12 mmol/L) 比对照组 (5.31 ± 1.4 mmol/L) 高得多.
- 在COVID-19患者中,高血糖症的风险较高 (OR = 1.86),特别是发烧或胃肠道症状.
- 这种关联在发烧 (OR = 3.59) 和胃肠道表现 (OR = 2.48) 的子组中明显.
结论:
- 轻度高血糖症在中度COVID-19感染的儿童中更为普遍.
- 当COVID-19出现发烧或胃肠道症状时,这种联系尤其明显.
- 研究结果表明,在儿科患者中,中度COVID-19和改变的葡萄糖代谢之间存在联系.
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