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一种新的自愈可降解共聚合物,基于聚酸和聚二氧化

Laifa Tong¹, Mi Zhou¹, Yulong Chen¹

¹Material Science and Engineering, College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310000, China.

Molecules (Basel, Switzerland)

|May 27, 2023

概括

研究人员通过Diels-Alder反应开发了一种新的可生物降解共聚合物,使用聚二氧化 (PPDO) 和聚酸 (PLA),实现自我愈合特性和更好的热稳定性.

科学领域:

聚合物化学聚合物化学
材料科学材料科学材料科学
生物材料是一种生物材料.

背景情况:

聚二松 (PPDO) 和聚酸 (PLA) 是具有不同特性的可生物降解聚合物.
结合PPDO和PLA可以产生具有增强特性的新材料.
在混合不混合的聚合物,如PPDO和PLA时,相分离是一个常见的挑战.

研究的目的:

通过Diels-Alder化学合成PPDO和PLA的新型生物降解共聚合物.
研究由此产生的共聚物质的自我愈合,结晶,热和降解特性.
为了克服通常在PPDO和PLA之间观察到的相隔问题.

主要方法:

通过Diels-Alder反应对PPDO和PLA进行共聚.
使用1H NMR,FT-IR和GPC对共聚物结构和分子量进行表征.
评估热性质 (DSC,POM,XRD),自我愈合 (风湿学测量) 和降解 (酶降解).

主要成果:

迪尔斯-阿尔德共聚合成功地防止了PPDO和PLA之间的相分离.
与PLA相比,DA4700共聚物表现出更高的结晶性能 (半结晶时间为2.8分钟).
DA共聚合物表现出增强的热稳定性 (Tm从93°C增加到103°C) 和显著的自我愈合能力.
发现DA共聚物的酶降解率在PPDO和PLA之间是中间的.

结论:

迪尔斯-阿尔德反应是一种有效的策略,用于创建具有集成自愈特性的PPDO-PLA共聚物.
合成的共聚合物提供了结晶,耐热性和生物降解性的可调节平衡.
这些新型可生物降解的自我修复共聚物具有先进材料应用的潜力.

关键词:

迪尔斯阿尔德反应结晶的行为结晶的行为聚二氧 (p-dioxanone) 是一种聚二氧.聚酸是一种多酸.它具有自我愈合的功能.

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