相关实验视频

Updated: Jul 29, 2025

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
07:20

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Published on: May 28, 2014

14.0K

新型生物化 (II) - 类复合物:二维和三维细胞毒性活性和机械洞察力

Stephen Barrett1, Michele De Franco2, Chiara Donati2

  • 1Department of Chemistry, Maynooth University, W23 NPY6 Maynooth, Ireland.

Molecules (Basel, Switzerland)
|May 27, 2023
PubMed
概括

合成和表征了具有生物素的新型铜 (II) 复合物. 这些化合物显示出作为抗癌剂的潜力,这是由于它们与DNA的相互作用和通过瘤细胞上的生物素受体的向传递.

关键词:
三维细胞培养的3D细胞培养.它具有抗癌活性,具有抗癌活性.生物生物是一种生物.复杂的铜 (II) 复合物.

更多相关视频

Quantifying the Binding Interactions Between CuII and Peptide Residues in the Presence and Absence of Chromophores11:38

Quantifying the Binding Interactions Between CuII and Peptide Residues in the Presence and Absence of Chromophores

Published on: April 5, 2022

2.5K
Anticancer Metal Complexes: Synthesis and Cytotoxicity Evaluation by the MTT Assay11:14

Anticancer Metal Complexes: Synthesis and Cytotoxicity Evaluation by the MTT Assay

Published on: November 10, 2013

57.8K

相关概念视频

Phase II Reactions: Miscellaneous Conjugation Reactions01:19

Phase II Reactions: Miscellaneous Conjugation Reactions

Phase II biotransformations are detoxification mechanisms that conjugate xenobiotics with endogenous substances, neutralizing their toxicity.
A key example involves the conjugation of cyanide ions, which impair cellular respiration and alter hemoglobin into non-oxygen-carrying cyanmethemoglobin. To neutralize this threat, a sulfur atom from thiosulphate is transferred to the cyanide ion, catalyzed by the enzyme rhodanese, resulting in an inactive compound called thiocyanate. The production of...
87
The Electron Transport Chain01:30

The Electron Transport Chain

The electron transport chain or oxidative phosphorylation is an exothermic process in which free energy released during electron transfer reactions is coupled to ATP synthesis. This process is a significant source of energy in aerobic cells, and therefore inhibitors of the electron transport chain can be detrimental to the cell's metabolic processes.
Inhibitors of the electron transport chain
Rotenone, a widely used pesticide, prevents electron transfer from Fe-S cluster to ubiquinone or Q...
17.0K