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日本捐赠人乳中的蛋白质和免疫成分含量:随妊娠和产后年龄的变化

Miori Tanaka¹, Midori Date¹, Kumiko Miura^1,2

¹The Nippon Foundation Human Milk Bank, 17-10 Nihonbashi-koamicho, Chuo-ku, Tokyo 103-0016, Japan.

|May 27, 2023

概括

供体母乳 (DHM) 为早产婴儿提供了必需的营养. 这项研究发现,孕期和产后年龄显著影响了日本DHM中的蛋白质,分泌免疫球蛋白A (sIgA) 和乳酸含量.

科学领域:

人母奶的成分人母奶的成分
新生儿营养新生儿营养
免疫学免疫学免疫学

背景情况:

捐赠人乳 (DHM) 是早产婴儿的重要营养来源,当母乳无法获得时.
人母乳的成分因母体因素而异,包括妊娠期和产后年龄.
在日本,关于DHM成分的数据有限,特别是关于其蛋白质和免疫成分.

研究的目的:

为了确定日本DHM的蛋白质和免疫成分 (分泌性免疫球蛋白A[sIgA]和乳酸铁素) 含量.
调查妊娠和产后年龄对DHM组成的影响.

主要方法:

分析了来自92名母亲的134个DHM样本,使用Miris人类牛奶分析仪检测蛋白质.
与酶相关的免疫吸收试验 (ELISA) 用于测量sIgA和乳铁素度.
统计分析以将营养水平与妊娠和产后年龄相关联.

主要成果:

前期的DHM显示出较高的蛋白质含量 (1.2g/dL) 与期末的DHM (1.0g/dL) 相比.
孕期DHM的sIgA含量 (110微克/毫升) 比孕前DHM (68.4微克/毫升) 高.
孕期年龄与蛋白质有负相关性,与sIgA和乳酸铁素有正相关性;产后年龄与所有测量组件有负相关性.

结论:

孕期和产后年龄显著影响日本DHM中的蛋白质,sIgA和乳二烯度.
这些发现强调了营养分析的必要性,以确保DHM在早产婴儿养中得到适当和安全的使用.
了解DHM组成的变化对于优化新生儿重症监护病房的营养支持至关重要.

关键词:

捐赠者母乳是人类的母乳.怀孕年龄怀孕年龄人类牛奶银行乳酸铁素是什么? 乳酸铁素是什么?在分娩后的一周.蛋白质蛋白质是蛋白质蛋白质的组成部分.这就是SIGAA的意思.

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