营养状况的评估及其对卵巢储备的影响:系统性审查
Laura Prieto-Huecas1, Clara Ángela Piera-Jordán1, Verónica Serrano De La Cruz-Delgado1
1Obstetrics and Gynaecology Service, Hospital Marina Salud, 03700 Denia, Spain.
Nutrients
|May 27, 2023
概括
营养状况影响卵巢储备. 高体重指数 (BMI) 对卵巢储备产生负面影响,卵子质量下降,生殖问题增加. 建议进一步研究特定的饮食因素.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 营养科学 营养科学
- 妇女健康 妇女健康
背景情况:
- 对影响生殖健康和生育能力的生活方式因素越来越感兴趣.
- 环境和生活方式因素,如压力,饮食和营养状况影响生殖健康.
- 营养状况越来越被认为是女性生育能力的关键决定因素.
研究的目的:
- 审查和综合当前关于营养状况对卵巢储备的影响的证据.
- 为改善生育年龄妇女生殖健康提供见解.
- 确定营养状况指标和卵巢储备标志物之间的关系.
主要方法:
- 系统的文献审查遵循PRISMA指南.
- 使用Cochrane协作风险偏见工具对包含的研究进行质量评估.
- 通过评估技术和报告的关系对数据的提取和合成进行了分类.
主要成果:
- 营养状况和卵巢储备之间的显著关系在超过一半的审查文章中 (54.5%) 发现.
- 在31.8%的研究中,增加的体重指数 (BMI) 与卵巢储备的减少有关,特别是如果BMI> 25在多囊性卵巢综合征患者.
- 在一些研究中,在卵巢储备和腰部比率之间观察到负相关性,而丸激素水平显示出积极的,但与BMI相关的关联.
结论:
- 营养状况显著影响卵巢储备.
- 体重指数升高会对卵巢储备产生负面影响,减少腹膜毛囊数量和抗穆勒激素水平,损害卵细胞质量.
- 需要进一步的研究来确定影响卵巢储备的特定饮食因素,并加强生殖健康策略.
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