改善对高风险老年人的地中海质营养计划的坚持:试点随机试验
Julia L Sheffler1, Dimitris N Kiosses2, Zhe He3
1Center for Translational Behavioral Science, College of Medicine, Florida State University, Tallahassee, FL 32306, USA.
Nutrients
|May 27, 2023
概括
地中海类营养 (MKN) 对老年人痴呆风险有希望. 使用动机面试和行为改变技术的坚持计划与单独的教育相比,改善了参与和坚持.
科学领域:
- 神经科学是一个神经科学.
- 营养科学 营养科学
- 行为科学 行为科学
背景情况:
- 地中海类营养 (MKN) 可能会影响与痴呆风险相关的神经生物学机制.
- 对于有记忆问题的老年人来说,坚持MKN可能具有挑战性.
- 美国国立卫生院的ORBIT模型被用来开发一个支持MKN在这个群体中的使用的程序.
研究的目的:
- 为老年人带有记忆问题的地中海质营养坚持 (MKNA) 计划进行试点.
- 使用随机设计,将MKNA程序与MKN教育 (MKNE) 程序进行比较.
- 评估MKNA计划的可行性,可接受性,遵守性和临床结果.
主要方法:
- 一个双臂随机试验,58名参与者经历了记忆问题.
- 在MKNA手臂中,纳入了动机面试 (MI) 和行为改变技术 (BCT).
- 主要结局包括可行性,可接受性,坚持性和临床结果.
主要成果:
- 观察到高课程完成率 (79%) 和保留率 (82%在MKNA和72%在MKNE).
- 在MKNA手臂显示了更高的MKN坚持和更好的会议出席率 (91%vs77%).
- 参与者报告高满意度;注意到一些临床益处,与坚持相关.
结论:
- 整合MI和BCT策略的MKN计划可以提高参与者的参与度和保留率.
- 无论是MKNA还是MKNE程序都是可行的,对于有记忆问题的老年人来说都是可以接受的.
- 需要进一步的研究来探索MKN坚持的长期临床益处.
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