临床表现,微生物学特征,以及它们对Xanthogranulomatous Pyelonephritis术后结果的影响:来自现实世界多中心实践的观点
Vineet Gauhar1, José Iván Robles-Torres2, Marcelo Langer Wroclawski3,4
1Department of Minimally Invasive Urology, Ng Teng Fong General Hospital, Singapore 609606, Singapore.
Pathogens (Basel, Switzerland)
|May 27, 2023
概括
桑托格拉诺瘤性肌炎 (XGP) 是一种罕见的脏感染,通常与尿路阻塞有关. 这项研究分析了365名XGP患者,发现高比例的阳性脏培养和常见的感染,如大肠杆菌.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 桑托格兰瘤性肌炎 (XGP) 是一种罕见的,慢性细粒状膜感染.
- XGP经常与长期的尿路阻塞有关,通常是由石头和感染引起的.
研究的目的:
- 分析诊断为XGP.患者的临床,实验室和微生物培养资料.
- 为了确定与XGP患者的阳性尿液培养相关的因素.
主要方法:
- 来自5个国家的10个中心 (2018-2022年) 经过组织病理学诊断的XGP患者的回顾性审查.
- 包括365名拥有完整病历的患者.
- 膀和尿培养结果,并发症和临床结果的分析.
主要成果:
- 大多数患者是女性 (62.5%),平均年龄为45岁.
- 慢性病是最常见的并发症 (71%);多种结石在34.5%中存在.
- 阳性尿培养高 (81.9%),大肠杆菌是最常见的病原体 (42.4%). 泌尿突发症发生在13.4%的患者中.
结论:
- 在XGP患者中,阳性膀尿液培养独立与尿道,复发性尿道感染,肌素升高和疾病扩散有关.
- 阳性培养的患者患贫血的频率明显高.
- 这些发现可以帮助泌尿科医生为接受切除术的XGP患者提供咨询.
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