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在慢性病毒感染期间,个体内皮质特异性CD8+ T细胞免疫反应的形状不同

Sebastian Klein1,2, Jasmin Mischke1,2, Finn Beruldsen3

  • 1Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.

Pathogens (Basel, Switzerland)
|May 27, 2023
PubMed
概括

慢性病毒感染的特征是CD8+ T细胞耗尽. 这项研究揭示了不同的T细胞受体 (TCR) 剧目疲和免疫检查点抑制剂 (ICI) 治疗反应在不同的病毒表位.

关键词:
CD8+ T 细胞 CD8+ T 细胞在T细胞受体谱中.检查点抑制剂治疗检查点抑制剂治疗慢性病毒感染 慢性病毒感染淋巴细胞冠状淋巴炎病毒.

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