使用眼科抗黄水瘤剂的使用模式,含有或不含防护剂:一个横截面研究
Luis Fernando Valladales-Restrepo1,2,3, María Camila Oyuela-Gutiérrez3, Ana Camila Delgado-Araujo1
1Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia, Universidad Tecnológica de Pereira-Audifarma S.A, Pereira 660003, Colombia.
Pharmaceuticals (Basel, Switzerland)
|May 27, 2023
概括
大多数青光眼患者使用含有防腐剂的多剂量眼药,如化. 固剂组合药物可以减少眼睛表面毒性,尽管治疗模式异质.
科学领域:
- 眼科医生 眼科 眼科
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 青光眼治疗的目的是降低眼内压力.
- 眼滴中的防腐剂,如化,可以引起眼睛表面的毒性.
- 了解抗瘤剂和防腐剂的使用对于患者的安全至关重要.
研究的目的:
- 确定在哥伦比亚患者中使用抗葡萄球瘤剂和眼科防腐剂的模式.
- 分析与眼治疗相关的社会人口统计和药理变量.
主要方法:
- 使用920万人口数据库进行横截面研究.
- 包括社会人口统计学和药理学变量.
- 进行了描述性和双变量统计分析.
主要成果:
- 在38,262名患者中,98.8%使用了多剂量抗葡萄糖瘤药物.
- 最常见的是前列腺素类似物 (59.9%) 和β-抑制剂 (59.2%).
- 94.1%的人使用了含有防腐剂的药物,主要是化 (68.4%).
- 固定剂量组合药物 (FDC) 在41.3%的联合疗法中使用.
结论:
- 哥伦比亚的玻璃眼治疗是异质的,但通常符合指南.
- 大多数患者接触过防腐剂,特别是化.
- 增加FDC药物的使用可能会减轻眼睛表面的毒性.
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