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在开发液晶纳米粒子作为药物输送系统的最新进展

Jassica S L Leu¹, Jasy J X Teoh¹, Angel L Q Ling¹

¹School of Pharmacy, International Medical University, Jalan Jalil Perkasa 19, Bukit Jalil, Kuala Lumpur 57000, Selangor, Malaysia.

|May 27, 2023

概括

由于其独特的结构,热型非状液晶纳米颗粒 (LCNPs) 提供了先进的药物输送. 研究重点是提高LCNP的制备,表征和药物释放,以提高治疗疗效.

科学领域:

纳米技术纳米技术
材料科学材料科学材料科学
生物医学工程生物医学工程

背景情况:

立方体和六体体等热型非状液晶纳米粒子 (LCNPs) 具有独特的结构特征,有利于药物输送.
这些纳米结构由表面活性剂稳定,具有大表面积用于治疗分子加载和可调节的孔径,影响药物释放动力学.

研究的目的:

审查用于药物输送应用的LCNP技术的最新进展.
探索LCNPs的新生物医学应用的设计策略.
总结基于给药途径和药理动力学调制的LCNP应用.

主要方法:

关于LCNP制备和表征的当前文献的审查.
对研究的分析,重点是从LCNPs控制的药物释放机制.
检查LCNP在各种管理途径中的应用及其对药理动学的影响.

主要成果:

由于其结构性质,LCNPs,如立方体和六体体,显示出作为药物输送载体的巨大潜力.
中相组合和毛孔大小的修改允许控制药物加载和释放配置文件.
目前正在进行的研究旨在优化LCNP的制备,表征和体内表现.

结论:

LCNPs代表了先进的药物输送系统具有可调节性质的有希望的平台.
对LCNP设计和应用的进一步研究可以导致革命性的生物医学解决方案.
在不同的施用途径中,LCNPs提供有效的药理动力学调制.

关键词:

立方体体的部分是立方体体.药物输送系统是药物输送系统.六体体体是指六体体体的组成部分.液晶纳米粒子 (LCNP) 是一种他们是天文学家.提供疫苗的疫苗.

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