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对精选的辅助剂对从高素矩阵片中释放卡维迪醇的影响进行比较研究

Tadej Ojsteršek1,2, Grega Hudovornik1, Franc Vrečer1,2

  • 1KRKA, d. d., Novo mesto, Šmarješka cesta 6, 8501 Novo Mesto, Slovenia.

Pharmaceutics
|May 27, 2023
PubMed
概括

这项研究研究了辅助剂如何影响从高糖 (HPMC) 矩阵片中释放的卡维迪醇. 对于水溶性辅助剂,POLYOXTM WSR N-80和Polyglykol® 8000 P提供了最佳控制,而AVICEL® PH-102和PH-200则在水溶性辅助剂方面表现出色.

关键词:
在HPMC中,HPMC是指HPMC.有控制释放的释放.直接压缩直接压缩.药物释放修饰剂 药物释放修饰剂辅助剂是一种辅助剂.延长释放放出的延长释放填充剂 填充剂 填充剂 填充剂过高蛋白质糖 (hypromellose) 是一种蛋白质.经过修改释放的释放方法长时间释放的释放.

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