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Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
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开发生物预测溶解方法,用于延长释放德斯文拉法辛片

Gustavo Vaiano Carapeto1, Marcelo Dutra Duque2, Michele Georges Issa1

  • 1Department of Pharmacy, Faculty of Pharmaceutical Sciences, Universidade de São Paulo-USP, Av. Prof. Lineu Prestes 580, São Paulo 05508-080, SP, Brazil.

Pharmaceutics
|May 27, 2023
PubMed
概括

使用实验设计 (DoE) 和基于生理学的生物制药建模 (PBBM) 开发了desvenlafaxine延长释放 (ER) 片的新生物预测溶解方法. 这种方法通过几乎预测生物等价性来降低仿制药开发风险.

关键词:
美国能源部 (DoE)美国的 PBBM PBBM塔古奇奇 (Taguchichi) 是一个非常有价值的人.生物预测溶解方法.尽管如此,lafaxine.

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