水中传播的肝炎E病毒感染的集群病例,法国
Sébastien Lhomme1,2, Sébastien Magne3, Sylvie Perelle4
1Centre National de Référence (CNR) des Virus des Hépatites à Transmission Entériques (Hépatite A et E), Laboratoire de Virologie, CHU Toulouse, 31300 Toulouse, France.
Viruses
|May 27, 2023
概括
一个法国村庄的肝炎E疫情被追溯到连接到公共网络的私人水源. 这项调查强调了私人供水污染农村地区公共网络的风险.
科学领域:
- 流行病学 流行病学
- 病毒学 病毒学
- 环境健康 环境健康
背景情况:
- 2015年4月,在法国的一个农村村庄发现了7例E型肝炎病毒 (HEV) 感染病例.
- 已启动调查以确认病例集群,并确定感染源.
研究的目的:
- 为了调查在法国农村村庄爆发的E型肝炎病毒 (HEV) 感染疫情.
- 为了确定HEV疫情的来源和传播途径.
- 评估供水在HEV传动中的作用.
主要方法:
- 使用RT-PCR和血清学测试发现活跃病例.
- 环境调查,包括对HEVRNA的水源检测.
- 对HEV菌株的遗传学分析.
主要成果:
- 确认了七例HEV病例,所有病例都与村庄有关.
- 遗传学分析揭示了属于HEV3f亚基因型的高度相似的HEV菌株.
- 公共供水中断与可能的感染期相吻合.
- 在连接到公共网络的私人水源中检测到HEV RNA,公共网络在休息期间供应水.
结论:
- 连接到公共网络的私人供水系统被确定为HEV污染的可能来源.
- 这次疫情强调了私人供水对农村公共卫生构成的风险.
- 确保私人水源与公共网络的适当断开,对于防止水传播疾病的传播至关重要.
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