托普莱斯核心压缩机调节了植物Physcomitrium的发育开关,这些开关对于植物的陆地化至关重要
Barry Causier1, Mary McKay1, Tayah Hopes1,2
1Centre for Plant Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.
The Plant journal : for cell and molecular biology
|May 27, 2023
概括
托普莱斯 (TPL) 核心压缩机对植物发育至关重要,它调节了古老的植物Physcomitrium patens的关键生长过渡. 这项研究揭示了TPL.
科学领域:
- 植物发育生物学植物发育生物学
- 进化生物学是进化的生物学.
- 转录法规 转录法规
背景情况:
- 转录核心压缩体的TOPLESS (TPL) 家族在血管精子发育中起着至关重要的作用.
- 在非angiosperm植物中,特别是 bryophytes 中,TPL 功能在很大程度上尚未被探索.
研究的目的:
- 为了研究TPL在菌体Physcomitrium patens中的功能,这是一个模型生物体,它在约50亿年前从血管苗分离出来.
- 了解PpTPL在基本发展过渡中的作用及其融入监管网络.
主要方法:
- 使用了转基因的Physcomitrium patens线,其PpTPL活性降低.
- 采用转录学来分析基因表达和调节网络.
- 研究的发育转换器包括chloronemata到caulonemata过渡和2D到3D生长.
主要成果:
- 减少的PpTPL活性显示,它在从色斑块转变为色斑块的过程中以及从二维到三维生长的过程中起着重要作用.
- 转录学将PpTPL集成到控制3D增长的监管网络中.
- 确定了PpTPL在黄类调节中的新型作用.
结论:
- PpTPLs是P. patens.中2D到3D发育切换的关键调节者.
- 作为一种古老的蛋白质家族,TPL被选择为发展途径,使植物能够殖民土地.
- 这项研究强调了TPL在植物陆地化中的保留和演变作用.
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