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定性嗅觉功能障碍的临床特征和相关因素
1Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Rhinology
|May 27, 2023
概括
定性嗅觉功能障碍,如帕洛斯米亚和斯米亚,与更高的嗅觉敏感性有关,但生活质量降低. 病毒感染是帕洛斯米亚的危险因素,而不是斯米亚.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经科学是一个神经科学.
- 嗅觉研究 嗅觉研究
背景情况:
- 质性嗅觉功能障碍 (OD),包括帕罗斯米亚和斯米亚,在COVID-19后越来越受到关注.
- 临床特征和定性OD的风险因素仍未得到充分研究.
研究的目的:
- 为了研究帕洛斯米亚和斯米亚的临床特征.
- 为了确定与这些定性嗅觉障碍相关的因素.
主要方法:
- 对753名患有主观嗅觉障碍的成年患者的回顾性分析.
- 评估包括嗅觉问卷和心理物理嗅觉功能测试.
- 人口统计和临床数据的分析是基于parosmia或phantosmia的存在.
主要成果:
- 8%的人报告了帕洛斯米亚,22.2%的人报告了幻影.
- 年龄较小和女性性别与这两种情况有关.
- 帕洛斯米亚在后病毒性OD中更频繁; 幻影的频率在病因学上是相似的.
- 患有帕洛斯米亚/斯米亚的患者具有更高的嗅觉敏感度 (TDI得分),但生活中更大的破坏.
- 两者的独立因素是年龄较小和TDI得分较高;病毒感染仅与有关.
结论:
- 帕洛斯米亚和斯米亚表明嗅觉敏感度增加,但生活质量下降.
- 病毒感染是帕洛斯米亚的危险因素,但不是斯米亚.
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