在儿科心脏导管术期间测量氧气消耗比假设的氧气消耗更准确
Bradford H Ralston1,2, Andrew T Waberski3, Joshua P Kanter4
1Division of Cardiology, Children's National Hospital, Washington, DC, USA. bradralston@gwu.edu.
Pediatric cardiology
|May 27, 2023
概括
测量氧气消耗 (mVO2) 比计算儿科心脏指数 (C.I.) 的假设值更准确. 通过菲克的方法. 这项研究验证了儿科导管治疗中的mVO2,比假定的VO2 (aVO2) 更准确.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 医疗器械技术 医疗器械技术
- 生理测量生理测量
背景情况:
- 心脏指数 (C.I.) 的心脏指数 使用Fick方法的计算通常依赖于假设的氧气消耗 (VO2) 由于未知值.
- 这种依赖假设的VO2 (aVO2) 引入了C.I.中的重大不准确性. 评估. 评估. 评价. 这是一个很好的方法.
- 准确的VO2测量对于在儿科心脏导管治疗中精确的血液动力学评估至关重要.
研究的目的:
- 使用CARESCAPE E-sCAiOVX模块验证测量氧耗 (mVO2) 的准确性,用于CI. 计算. 计算. 这是一个很好的方法.
- 为了比较mVO2的准确性与儿科导管患者群体中假定的VO2 (aVO2) 的准确性.
- 评估mVO2在较年轻的儿科患者 (<36个月) 的性能.
主要方法:
- 测量VO2 (mVO2) 是从接受全身麻醉和控制通风心脏导管治疗的儿科患者收集的.
- 使用心脏MRI (cMRI) 或热稀释 (TD) 作为参考标准,mVO2与通过逆Fick方法确定的参考VO2 (refVO2) 进行了比较.
- 分析了mVO2和refVO2,以及aVO2和refVO2之间的一致性,相关性和偏差.
主要成果:
- 总共获得了193个VO2测量;71个有相应的cMRI或TD数据用于验证.
- mVO2与refVO2 (ρc=0.73,r2=0.63) 显示出良好的一致性和相关性,平均偏差为-3.2%.
- 假设的VO2 (aVO2) 显示出明显较弱的一致性和相关性 (ρc=0.28,r2=0.31),平均偏差为+27.5%,在年幼儿童中表现不佳.
结论:
- 使用CARESCAPE E-sCAiOVX模块测量的氧气消耗 (mVO2) 比CI的假设VO2 (aVO2) 准确得多. 在儿科导管治疗中的计算.
- 使用mVO2可以提高CI的准确性. 确定,特别是在更年轻的儿科患者中,因为aVO2的预测模型不太可靠.
- 实施mVO2测量为儿科心脏手术中血液动力学评估提供了更精确的方法.
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