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Updated: Jul 29, 2025

Isolation of Primary Patient-specific Aortic Smooth Muscle Cells and Semiquantitative Real-time Contraction Measurements In Vitro
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Published on: February 15, 2022

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sGC激动剂BAY1021189通过加速血管光滑肌细胞表型切换器来促进胸前大动脉剖析的形成

Hongcheng Jiang1, Yue Jiang2, Yunkun Qu3

  • 1Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy, Wuhan, 430030, Hubei, China.

European journal of pharmacology
|May 27, 2023
PubMed
概括

可溶性甲基酸环酶-蛋白激酶G1 (sGC-PRKG1) 信号通过改变血管光滑肌细胞 (VSMCs) 来促进胸前大动脉剖析 (TAD). 这一途径加速了VSMC表型切换,导致TAD形成和高死亡率.

关键词:
现象型开关 现象型开关蛋白激酶cGMP依赖的1型蛋白激酶可溶性瓜尼酸环酸酶是什么?胸前大动脉切割血管光滑肌肉细胞细胞

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