M2巨细胞通过TGF-β/PI3K/Akt通路调节天体细胞偏振的机制

Qi-Ming Pang1, Qian Zhang2, Xiang-Chong Wu3

  • 1Key Laboratory of Cell Engineering of Guizhou Province, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China; Department of Orthopaedic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Immunology letters
|May 27, 2023
PubMed
概括

将星体细胞 (AS) 转化为神经保护性A2表型对于脊髓损伤的修复至关重要. 这项研究表明,M2巨细胞中的TGF-β激活PI3K/Akt通路,驱动A2星球细胞两极分化.

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