研究预注册:衡量重要因素:为儿科焦虑障碍和临床试验开发和传播一个核心结果集
Suneeta Monga1, Riddhi Desai2, Samantha J Anthony1
1Hospital for Sick Children, and the University of Toronto, Ontario, Canada.
概括
在儿科焦虑临床试验中标准化结果测量对于改善研究翻译至关重要. 在COMPACT倡议将开发一个核心成果集 (COS) 在儿科焦虑研究的一致测量.
科学领域:
- 儿童和青少年精神病学 儿童和青少年精神病学
- 临床心理学 临床心理学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 儿科焦虑症 (AD) 显著影响儿童的生活.
- 目前的研究面临的挑战是由于结果的选择,测量和报告不一致.
- 标准化是必要的,以改善研究结果转化为临床实践.
研究的目的:
- 为儿科焦虑临床试验开发一个协调的,基于证据和共识的核心结果集 (COS).
- 确保COS对青年和家庭有意义.
- 解决儿科阿尔茨海默病研究结果测量的异质性.
主要方法:
- 该研究概述了核心成果集 (COS) 的发展.
- 这包括在临床试验中创建一组最小的结果,以便在临床试验中进行一致的测量和报告.
- 该倡议旨在基于证据和共识的方法.
主要成果:
- 建立了儿童焦虑临床试验 (COMPACT) 倡议的核心结果和措施.
- 该倡议将制定一个标准化的核心成果集 (COS).
- 这种COS将在未来的儿科焦虑临床试验中使用.
结论:
- 标准化的核心结果集 (COS) 对于推进儿科焦虑研究至关重要.
- 在COMPACT倡议的COS将提高研究的一致性和可比性.
- 这种标准化将有助于将研究转化为有效的儿科焦虑临床实践.
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