关于植物化合物在治疗人类免疫缺陷病毒中的作用的全面概述
Chinmayee Priyadarsani Mandhata1, Chita Ranjan Sahoo1, Rabindra Nath Padhy1
1Central Research Laboratory, Institute of Medical Sciences and SUM Hospital, Siksha O Anusandhan Deemed to be University, Bhubaneswar, Odisha 751003, India.
Journal of integrative medicine
|May 27, 2023
概括
需要新的药物来对抗人类免疫缺陷病毒 (HIV) 流行病. 本综述探讨了植物衍生化合物作为艾滋病毒的有希望的自然治疗方法.
科学领域:
- * 病毒学和天然产品化学
- * 药物发现和开发
背景情况:
- *获得性免疫缺陷综合征 (艾滋病) 仍然是一个由人类免疫缺陷病毒 (HIV) 驱动的全球健康危机.
- *目前的抗病毒疗法面临的挑战是病毒耐药性和病毒储存库的持久性.
- * 迫切需要针对艾滋病毒的新,安全和有效的治疗策略.
研究的目的:
- * 审查当前的艾滋病毒治疗格局,重点关注对新型治疗剂的需求.
- * 探索天然产品的潜力,特别是植物衍生化合物 (植物化合物),作为抗艾滋病毒剂.
- * 突出最近在使用天然化合物进行HIV干预方面的进展和有希望的结果.
主要方法:
- *对科学数据库和期刊进行全面的文献综述.
- *分析了关于植物衍生生物活性化合物的研究,报告了抗艾滋病毒活性.
- *综合有关艾滋病毒,当前治疗方式和基于天然产品的治疗方法的信息.
主要成果:
- *植物衍生化合物显示出显著的潜力,作为制药架,用于开发抗艾滋病毒药物.
- *天然产品为克服常规疗法观察到的抗药性模式提供了一个有希望的途径.
- *许多植物化合物在体外和体内表现出抗HIV活性,需要进一步调查.
结论:
- *植物化合物是开发新型和有效的抗艾滋病毒治疗方法的宝贵资源.
- * 对自然来源的持续研究对于发现新型抗艾滋病毒药物和对抗疫情至关重要.
- *将天然产品研究纳入艾滋病毒治疗策略中,可能会导致更可持续和更容易获得的疗法.
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