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Updated: Jul 29, 2025

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在转移性前列腺癌中,PARP抑制剂是否已准备好首次使用? 也许不是也许不是

Daniel A González-Padilla1, José Daniel Subiela2

  • 1Department of Urology, Clínica Universidad de Navarra, Madrid, Spain.

European urology
|May 27, 2023
PubMed
概括

PARP 抑制剂在前列腺癌中表现出活性,但不能改善存活率. 由于研究的局限性,建议在没有BRCA1/2突变的患者中谨慎使用.

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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