膀容量和成长在经典的膀外缩:一个新的预测工具
Mahir Maruf1, Jiafeng Zhu2, Ahmad Haffar1
1Robert D. Jeffs Division of Pediatric Urology, James Buchanan Brady Urological Institute, Douglas A. Canning MD Exstrophy Database Center, Charlotte Bloomberg Children's Hospital, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Journal of pediatric urology
|May 27, 2023
概括
这项研究为经典膀外缩 (CBE) 患者开发了一种膀容量名图,提高了手术规划和禁欲手术的预测准确度. 诺米图利用现有的临床因素来改善患者管理.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 膀外缩的外科治疗方法
- 尿失禁预测 尿失禁预测
背景情况:
- 膀容量 (BC) 对于管理经典膀外缩 (CBE) 患者至关重要.
- BC影响了像膀部重建 (BNR) 这样的禁欲手术的资格.
- 准确的BC预测对于优化外科手术结果和实现尿失禁至关重要.
研究的目的:
- 为了开发一个预测的膀容量 (BC) 膀外缩症 (CBE) 患者的预测性脑谱.
- 为BC预测利用易于访问的临床参数.
- 为患者和儿科泌尿科医生提供一个工具来估计BC.
主要方法:
- 对一个机构的CBE患者数据库的回顾性审查.
- 使用线性混合效应模型开发预测模型.
- 包括诸如初级关闭结果,性别,关闭时的年龄和关闭以来的时间等因素.
主要成果:
- 开发了一个名图,包括初级关闭结果,性别,关闭时的年龄和关闭后的时间.
- 该模型显示,与基于年龄的科夫方程相比,预测准确度有所提高.
- 该名录可作为一个基于网络的工具用于临床应用.
结论:
- 发达的膀容量诺米图为CBE患者提供了更准确的预测.
- 诺米图利用可访问的临床数据来改进外科手术规划.
- 建议进一步进行多中心验证,以便广泛采用此CBE膀生长名录.
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