大脑的调节程序早于中枢神经系统的进化
Dylan Faltine-Gonzalez1, Jamie Havrilak1, Michael J Layden2
1Department of Biological Sciences, Lehigh University, Bethlehem, PA, USA.
Scientific reports
|May 27, 2023
概括
大脑模式的相似性可能来自于融合进化,而不是同源性. 保存的前后后轴程序早于大脑,这表明它是在神经系统集中化期间被选择的.
科学领域:
- 进化发育生物学 进化发育生物学
- 神经科学是一个神经科学.
- 进行比较的基因组学.
背景情况:
- 了解集中神经系统的演变是确定大脑起源的关键.
- 沿前后轴保存的基因表达模式表明大脑同质性.
- 另一种假设是通过轴向程序的合作选择提出了融合进化.
研究的目的:
- 为了研究神经发生过程中轴向程序的演变.
- 解决共享的大脑模式是否反映了趋同或同质性的问题.
- 为了测试轴向程序在神经系统进化过程中被合作的假设.
主要方法:
- 在cnidarians和bilaterians中对基因表达模式的比较分析.
- 调查前后轴程序在神经发生过程中的作用.
- 在Nematostella进行功能研究,以评估轴向程序功能.
主要成果:
- 双边前后部程序在口腔-腹腔轴线沿着骨髓神经网络形成模式.
- 前后后的程序在cnidarian-bilaterian共同祖先的发育神经系统中进行了区域化.
- 这表明轴向程序早于大脑的出现.
结论:
- 分享的大脑模式并不是大脑同质性的充分证据.
- 轴向程序可能早于大脑,并在神经系统集中化期间被采用.
- 这支持了对大脑模式相似性的融合进化假设.
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